GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs6050566 | chr20:25351071 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000547 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050566 | chr20:25351071 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.44 | 8.47E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050566 | chr20:25351071 | NINL | chr20:25433338-25566153:- | 0.34 | 7.05 | 6.43E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050566 | chr20:25351071 | PYGB | chr20:25228706-25278647:+ | 0.14 | 3.59 | 0.000363 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050573 | chr20:25366065 | ENTPD6 | chr20:25176339-25207360:+ | -0.32 | -7.36 | 8.11E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050573 | chr20:25366065 | FAM182A | chr20:26035250-26067552:+ | -0.19 | -3.49 | 0.000534 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050573 | chr20:25366065 | FAM182B | chr20:25744102-25848786:- | 0.25 | 5.29 | 1.86E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050573 | chr20:25366065 | NINL | chr20:25433338-25566153:- | -0.33 | -6.77 | 3.69E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050573 | chr20:25366065 | PYGB | chr20:25228706-25278647:+ | -0.16 | -4.03 | 6.61E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050590 | chr20:25384994 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.24 | 1.82E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050590 | chr20:25384994 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000541 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050590 | chr20:25384994 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.4 | 1.07E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050590 | chr20:25384994 | NINL | chr20:25433338-25566153:- | 0.33 | 6.9 | 1.65E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050590 | chr20:25384994 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.03 | 6.52E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050598 | chr20:25397257 | ENTPD6 | chr20:25176339-25207360:+ | -0.31 | -7.19 | 2.5E-12 | Liver enzyme levels (alkaline phosphatase) |